Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Mania
ADR ID BADD_A02660
ADR Hierarchy
19      Psychiatric disorders
19.16      Manic and bipolar mood disorders and disturbances
19.16.02      Mood alterations with manic symptoms
19.16.02.002      Mania
Description A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood. [CTCAE] A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. [MeSH]
MedDRA Code 10026749
MeSH ID D001714; D001714; D001714
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute mania | Atypical manic disorder | Change to manic state | Mania | Mania acute | Mania aggravated | Manic | Manic disorder, recurrent episode | Manic disorder, recurrent episode, in full remission | Manic disorder, recurrent episode, in partial or unspecified remission | Manic disorder, recurrent episode, mild degree | Manic disorder, recurrent episode, moderate degree | Manic disorder, recurrent episode, severe degree, specified as with psychotic behavior | Manic disorder, recurrent episode, severe degree, specified as with psychotic behaviour | Manic disorder, recurrent episode, severe degree, without mention psychotic behavior | Manic disorder, recurrent episode, severe degree, without mention psychotic behaviour | Manic disorder, recurrent episode, unspecified degree | Manic disorder, single episode | Manic disorder, single episode, in full remission | Manic disorder, single episode, in partial or unspecified remission | Manic disorder, single episode, mild degree | Manic disorder, single episode, moderate degree | Manic disorder, single episode, severe degree, specified as with psychotic behavior | Manic disorder, single episode, severe degree, specified as with psychotic behaviour | Manic disorder, single episode, severe degree, without mention of psychotic behavior | Manic disorder, single episode, unspecified degree | Manic episode | Manic excitement | Manic psychosis | Manic reaction | Manic state | Manic state aggravated | Oppression to conduct act | Psychosis manic | Reaction manic | Bipolar Disorder | Bipolar Disorders | Disorder, Bipolar | Psychosis, Manic-Depressive | Psychosis, Manic Depressive | Manic-Depressive Psychosis | Manic Depressive Psychosis | Affective Psychosis, Bipolar | Bipolar Affective Psychosis | Psychoses, Bipolar Affective | Psychosis, Bipolar Affective | Psychoses, Manic-Depressive | Manic-Depressive Psychoses | Psychoses, Manic Depressive | Manias | Manic State | Manic States | State, Manic | States, Manic | Depression, Bipolar | Bipolar Depression | Manic Disorder | Disorder, Manic | Manic Disorders
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01736Pergolide mesylate--
BADD_D01750Phenelzine--
BADD_D01751Phenelzine sulfate--
BADD_D01817Pramipexole0.002189%
BADD_D01818Pramipexole dihydrochloride--
BADD_D01833Prednisolone sodium phosphate--
BADD_D01834Prednisone0.000119%
BADD_D01835Pregabalin--
BADD_D01856Propafenone--
BADD_D01857Propafenone hydrochloride--
BADD_D01867Propranolol0.000253%
BADD_D01888Quetiapine0.004967%
BADD_D01889Quetiapine fumarate--
BADD_D01913Ranitidine--
BADD_D01916Rasagiline mesylate--
BADD_D01919Reboxetine--
BADD_D01933Ribavirin0.072524%
BADD_D01942Riluzole--
BADD_D01951Risperidone0.004290%
BADD_D01952Ritonavir--
BADD_D01955Rivastigmine0.002484%
BADD_D01966Ropinirole--
BADD_D02002Selegiline--
BADD_D02010Sertraline0.001602%
BADD_D02011Sertraline hydrochloride--
BADD_D02016Sibutramine--
BADD_D02017Sibutramine hydrochloride--
BADD_D02047Sodium oxybate0.003633%
BADD_D02053Sofosbuvir0.002893%
BADD_D02062Sparfloxacin--
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